Study Findings on Acinetobacter baumannii Published by Researchers at Cairo University (Exploring the antimicrobial activity of Origanum majorana L. against the highly virulent multidrug-resistant Acinetobacter baumannii AB5075: UPLC-HRMS...).

Researchers at Cairo University have conducted a study exploring the antimicrobial activity of Origanum majorana L. against the highly virulent multidrug-resistant Acinetobacter baumannii. The study found that O. majorana L. exhibited significant growth inhibitory effects on A. baumannii, particularly the polar 50% methanol fraction. The researchers identified 29 metabolites in the bioactive fraction, with justicidin B being the most highly scoring metabolite for binding with molecular targets in A. baumannii. The study suggests that O. majorana L. extract, specifically justicidin B, inhibits the growth of A. baumannii by targeting its fatty acid synthesis. [Extracted from the article]