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Clinical applications and challenges of metagenomic next-generation sequencing in the diagnosis of pediatric infectious disease.
- Source :
- Journal of Laboratory Medicine; Jun2024, Vol. 48 Issue 3, p97-106, 10p
- Publication Year :
- 2024
-
Abstract
- Infectious diseases seriously threaten the lives of children. Timely and accurate detection of pathogenic microorganisms and targeted medication are the keys to the diagnosing and treatment of infectious diseases in children. The next-generation metagenomic sequencing technology has attracted great attention in infectious diseases because of its characteristics such as no culture, high throughput, short detection cycle, wide coverage, and a good application prospect. In this paper, we review the studies of metagenomic next-generation sequencing in pediatric infectious diseases and analyze the challenges of its application in pediatric diseases. [ABSTRACT FROM AUTHOR]
- Subjects :
- RESPIRATORY disease diagnosis
COMMUNICABLE disease diagnosis
GENOMICS
MEDICAL technology
MICROBIAL sensitivity tests
RESPIRATORY diseases
FEVER
PEDIATRICS
CLINICAL pathology
SEPSIS
NUCLEIC acids
ETIOLOGY of diseases
CENTRAL nervous system diseases
EXTRACELLULAR space
SEQUENCE analysis
MICROBIOLOGICAL techniques
MYCOBACTERIUM tuberculosis
CHILDREN
Subjects
Details
- Language :
- English
- ISSN :
- 25679430
- Volume :
- 48
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Journal of Laboratory Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 177660450
- Full Text :
- https://doi.org/10.1515/labmed-2023-0158