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Butyrate dietary supplementation promotes tolerant responses in a Pru p 3‐anaphylactic mouse model.

Authors :
Cruz‐Amaya, Anyith
Martín‐Astorga, María del Carmen
Lebrón‐Martín, Clara
Paris, Juan Luis
Céspedes, José Antonio
Núñez, Rafael
Torres, María José
Aranda, Carlos José
Cañas, José Antonio
Mayorga, Cristobalina
Source :
Allergy; Jun2024, Vol. 79 Issue 6, p1605-1608, 4p
Publication Year :
2024

Abstract

This article discusses the potential use of butyrate dietary supplementation as a treatment for plant-food allergies, specifically focusing on the allergen Pru p 3 found in peaches. The study conducted experiments on mice and found that butyrate supplementation promoted a tolerogenic environment by increasing the percentage of tolerogenic dendritic cells and regulatory T cells. These findings suggest that butyrate supplementation may be a promising alternative therapy for food allergies. However, further research is needed to determine the long-term effects and efficacy of butyrate supplementation in promoting tolerance. [Extracted from the article]

Details

Language :
English
ISSN :
01054538
Volume :
79
Issue :
6
Database :
Complementary Index
Journal :
Allergy
Publication Type :
Academic Journal
Accession number :
177612923
Full Text :
https://doi.org/10.1111/all.16033