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Advances in the Pathogenesis of Metabolic Liver Disease-Related Hepatocellular Carcinoma.

Authors :
Pinggui Chen
Yaoxuan Li
Yunyan Dai
Zhiming Wang
Yunpeng Zhou
Yi Wang
Gaopeng Li
Source :
Journal of Hepatocellular Carcinoma; Mar2024, Vol. 11, p581-594, 14p
Publication Year :
2024

Abstract

Hepatocellular carcinoma (HCC) is the sixth most common cancer globally and the primary cause of death in cancer cases, with significant public health concern worldwide. Despite the overall decline in the incidence and mortality rates of HCC in recent years in recent years, the emergence of metabolic liver disease-related HCC is causing heightened concern, especially in countries like the United States, the United Kingdom, and P.R. China. The escalation of metabolic liver disease-related HCC is attributed to a combination of factors, including genetic predisposition, lifestyle choices, and changes in the living environment. However, the pathogenesis of metabolic liver disease-associated HCC remains imperfect. In this review, we encapsulate the latest advances and essential aspects of the pathogenesis of metabolic liver disease-associated HCC, including alcoholic liver disease (ALD), metabolic dysfunction-associated steatotic liver disease (MASLD), and inherited metabolic liver diseases. [ABSTRACT FROM AUTHOR]

Details

Language :
English
Volume :
11
Database :
Complementary Index
Journal :
Journal of Hepatocellular Carcinoma
Publication Type :
Academic Journal
Accession number :
177527419
Full Text :
https://doi.org/10.2147/JHC.S450460