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Retrospective Analysis of Fever in Pediatric Age: Our Experience over the Last 5 Years.
- Source :
- Children; May2024, Vol. 11 Issue 5, p539, 14p
- Publication Year :
- 2024
-
Abstract
- Background: Fever is one of the most frequent symptoms highlighted during medical assistance. Due to this great impact, our study has the purpose of analyzing the demographic and laboratory characteristics of patients hospitalized in our center and identifying predictive markers to make the differential diagnosis between infectious and non-infectious fever. Methods: Our population included 220 children, collected from January 2017 to August 2022, hospitalized for continuous fever (4 days or more in duration with at least one temperature peak ≥37.5 °C) and excluded cases of discharge against medical advice and/or transfer to other operating units. Demographic (mean age at the time of admission, frequency of hospitalization, and mean days of hospitalization), laboratory, and instrumental variables were analyzed in order to find correlation with fever etiology. Results: Older age at the time of hospitalization, family history of periodic fever, fever lasting more than 8 days, and longer hospitalization are strongly associated with non-infectious fever, together with anemia, high platelet count, high CRP and ferritin, and hyponatremia at the time of admission. Paracetamol is the preferred antipyretic treatment. Echocardiogram has shown anomalies in patients with infectious fever, while ECG anomalies were detected in non-infectious fever. Conclusions: Our data underline the importance of predictive markers, such as clinical and laboratory parameters, to differentiate infectious from non-infectious fevers, but further studies are necessary. [ABSTRACT FROM AUTHOR]
- Subjects :
- STATISTICAL correlation
ANEMIA
DIFFERENTIAL diagnosis
PLATELET count
FERRITIN
PREDICTION models
T-test (Statistics)
HOSPITAL care
MEVALONATE kinase deficiency
FEVER
RETROSPECTIVE studies
DESCRIPTIVE statistics
FAMILY history (Medicine)
DNA
CHI-squared test
CLINICAL pathology
MEDICAL records
ACQUISITION of data
RESEARCH
HYPONATREMIA
NONOPIOID analgesics
DATA analysis software
COMPARATIVE studies
BIOMARKERS
C-reactive protein
ACETAMINOPHEN
ECHOCARDIOGRAPHY
CHILDREN
Subjects
Details
- Language :
- English
- ISSN :
- 22279067
- Volume :
- 11
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Children
- Publication Type :
- Academic Journal
- Accession number :
- 177498974
- Full Text :
- https://doi.org/10.3390/children11050539