A Clinical Trial Examined the Effectiveness of Curcumin and Vitamin C Sheets as Local Medicine Delivery Agents in Addition to Scaling and Root Planning.

Aim: The aim of this study was to assess the effectiveness of using Vitamin C and curcumin sheets applied subgingivally in combination with scaling and root planing (SRP). Patients age between 35 and 60 would be included, a total of 45 sites divided into three groups which are distributed as follows: Group I - (SRP) alone, Group II (SRP) with Vitamin C sheet, and Group III (SRP) with curcumin sheet Results: The mean gingival index (GI) scores for Group I were 2.60, 0.51, 0.93, 0.26, and 1.00, respectively, at baseline, 15 days, and 30 days. At baseline, the mean GI score in Group II decreased from 2.53 ± 0.52 to 0.67 ± 0.49 at 45 days. In line with this, Group III saw a decrease in the mean GI score from 3.00 ± 0.00 at baseline to 0.20 ± 0.41 at 45 days. At different points, each group showed a statistically significant difference. In Group III, the mean plaque index score dropped from 3.00 ± 0.00 at baseline to 0.27 ± 0.46 at 30 days. Only Group III showed a statistically significant difference at various periods. Probing pocket depth intergroup comparisons for all groups were found to be statistically significant. Conclusion: According to the study's findings, SRP in combination with Vitamin C and curcumin sheets improved periodontal markers and had a positive impact on individuals with chronic periodontitis. [ABSTRACT FROM AUTHOR]