Cyclin D1 expression in penile cancer.

A research paper titled "Cyclin D1 expression in penile cancer" was recently published in Oncotarget's Volume 15. The study, conducted by researchers from various universities in Brazil, aimed to analyze the expression of cyclin D1 in patients with penile cancer (PC) and determine its correlation with clinical and histopathological features. The study involved 100 PC patients and found that the absence of cyclin D1 expression was associated with HPV-positive histological subtypes, while its expression was associated with high-grade tumors, histological subtype, presence of sarcomatoid transformation, and perineural invasion. The researchers suggest that cyclin D1 may be a potential biomarker for PC, particularly for poorer prognosis. [Extracted from the article]