Are 25-hydroxyvitamin D deficiency and Helicobacter pylori infection more common in obese people?

Objective: Introduction: Our study aimed to show the significant relationship between Helicobacter pylori (Hp) positivity and 25-hydroxy vitamin D deficiency in obese individuals. Materials and Methods: Patients over the age of 20 who applied to the internal medicine department with dyspeptic complaints between January 1, 2019, and December 31, 2019, were divided into three groups as 18-24.9 (normal weight), 25-29.9 (overweight), 30-39.9 (obese) according to their body mass indexes (BMI). Urea breath test for Hp infection, 25-hydroxyvitamin D and other biochemical parameters, anthropometric measurements, education levels, systemic diseases, smoking history of patients who did not use proton pump inhibitor, and 25-hydroxyvitamin D for the last six months were retrospectively analyzed from the patient file archive. Results: The study was carried out with 632 cases, 51.6% (n = 326) of the patients were male, and 48.4% (n = 306) were female. The ages of the cases ranged from 21 to 65, and the mean age was 43.97 ± 12.87 years. Body mass index measurements of the cases included in the study ranged between 18.8 and 39.9 kg/m², with a mean of 28.02 ± 4.98 kg/m₂; %31.3% (n = 198) were normal weight, 35.5% (n = 224) were overweight and 33.2% (n = 210) were obese. Conclusion: We think that vitamin D deficiency should be eliminated for eradication treatment in Hp positive individuals, and Hp should be investigated closely in obese people. We want to state that the study will contribute to studies on the relationship between Hp and vitamin D deficiency in obese people in the literature. [ABSTRACT FROM AUTHOR]