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STUDY OF THE CHEMICAL COMPONENTS OF CO2 EXTRACTS FROM THE FRUITS OF SORBUS AUCUPARIA L.

Authors :
Mombekov, Serzhan
Datkhayev, Ubaidilla
Dosmagulova, Kalamkul
Kozhamzharova, Assel
Baidullayeva, Ainash
Mukhamejan, Assel
Kantureyeva, Aigerim
Yessimsiitova, Zura
Yussayeva, Damira
Beken, Zaure
Kydyrkhanova, Akmaral
Karbozova, Aidana
Zhuravel, Iryna
Source :
ScienceRise: Pharmaceutical Science; 2024, Vol. 48 Issue 2, p83-89, 7p
Publication Year :
2024

Abstract

The article presents the results of the study of the chemical composition of Sorbus aucuparia L. CO<subscript>2</subscript> subcritical extract. For the first time in Kazakhstan, 20 grams of brown Sorbus aucuparia L. extract were collected using subcritical carbon dioxide extraction. The current study was directed mainly to the chemical compositions of subcritical Sorbus aucuparia L. CO<subscript>2</subscript> subcritical extract. The Sorbus aucuparia L. extract's chemical compositions were determined using gas chromatography/mass spectrophotometry (GC-MS). The extract included the following main compounds: 5-Methyl-2(3H)-furanone (30.18 %), 5-(3-Ethoxy-4,5-dihydro-isoxazol-5-yl)-5-methyl-imidazolidine-2,4-dione (3.20 %), 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl (2.53 %). Determined fatty acid profile and the moisture content of raw vegetable ingredients of Sorbus substance. Quantitative determination of fatty acids of ethanol extract was carried out. The results of the analysis for fatty acids in the study showed that linoleic (37.7 %) and oleic (50.5 %) were the most prominent fatty acids. The aim of this study is to determine the component composition by using the GC-MS method and fatty acid to study the Sorbus aucuparia L. extract obtained by CO<subscript>2</subscript> extraction, which grows in Kazakhstan. Materials and methods. To determine the possibility of using Sorbus aucuparia L., we carried out the composition and fatty acid of the extract obtained by CO<subscript>2</subscript> extraction in subcritical conditions of Sorbus aucuparia L. by a certain GC-MS method. Results. The raw materials of the plant were collected in accordance with GACP requirements. Conducted subcritical CO<subscript>2</subscript> extraction of plant raw materials showed a 20 g extraction yield. Chemical compounds were discovered, bioactive components were identified, such as 5-Methyl-2(3H)-furanone (30.18 %), 5-(3-Ethoxy-4,5-dihydro-isoxazol-5-yl)-5-methyl-imidazolidine-2,4-dione (3.20 %), 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl (2.53 %). Conclusions. The possibility of using the obtained CO<subscript>2</subscript> extract of Sorbus aucuparia L. in the field of pharmaceutical products as a substance and a drug [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
25194844
Volume :
48
Issue :
2
Database :
Complementary Index
Journal :
ScienceRise: Pharmaceutical Science
Publication Type :
Academic Journal
Accession number :
177211649
Full Text :
https://doi.org/10.15587/2519-4852.2024.303000