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A Novel Process for the Key Intermediate of Fluoroquinolones.

Authors :
Yin, Kai
Yin, Xin
Wu, Wenliang
Wu, Hao
He, Xubin
Zhang, Yiwei
Source :
Organic Preparations & Procedures International; 2024, Vol. 56 Issue 3, p271-276, 6p
Publication Year :
2024

Abstract

This article discusses the synthesis of key intermediates for the production of fluoroquinolones, a group of antibiotics. The article compares two existing synthetic routes for these intermediates and highlights their limitations. The authors then propose a new synthetic route that utilizes a cheaper starting material and achieves a higher overall yield. The new route is described in detail, including the experimental procedures and results. The authors acknowledge the financial support they received for this research. [Extracted from the article]

Details

Language :
English
ISSN :
00304948
Volume :
56
Issue :
3
Database :
Complementary Index
Journal :
Organic Preparations & Procedures International
Publication Type :
Academic Journal
Accession number :
177179084
Full Text :
https://doi.org/10.1080/00304948.2023.2294655