Findings from University of Michigan Provide New Insights into Clinical Neurophysiology (High-definition Tdcs Over Primary Motor Cortex Modulates Brain Signal Variability and Functional Connectivity In Episodic Migraine).

A recent study conducted at the University of Michigan investigated the effects of high-definition transcranial direct current stimulation (HD-tDCS) on brain signal variability and functional connectivity in the trigeminal pain pathway of episodic migraine patients. The study found that active HD-tDCS reduced blood-oxygenation-level-dependent (BOLD) signal variability in certain areas of the brain, while increasing variability in others. Connectivity between different brain regions also changed as a result of the treatment. These findings suggest that HD-tDCS may have the potential to alleviate migraine headache attacks by modulating brain activity. The research was supported by the National Institutes of Health and has been peer-reviewed. [Extracted from the article]