Patent Issued for Substituted phenazines and methods of treating cancer and bacterial diseases (USPTO 11958842).

A recently issued patent discusses the development of substituted phenazines and their potential use in treating cancer and bacterial diseases. The patent focuses on the creation of novel ionophores that can act as anti-neoplastic and anti-infective agents. Specifically, the invention aims to address the need for new drugs in leukemia therapy and combat antimicrobial resistance. The patent also highlights the use of N-heterocyclic aromatic compounds as potent biological agents. It describes the discovery of phenazine derivatives with improved properties that can be utilized in the treatment of cancer and bacterial infections. The patent includes claims for combination products and pharmaceutical compositions containing these derivatives, as well as methods for treating bacterial and fungal infections. It provides a comprehensive list of bacteria and fungi that the derivatives can target. The patent was filed in April 2021 and published in April 2024. [Extracted from the article]