Reply to correspondence "Extracellular vesicle microRNA signatures as novel biomarkers in obese asthmatics".

This document is a reply to a correspondence letter regarding a scientific study on obese asthmatics. The authors clarify that their primary aim was to gain insights into the underlying mechanisms of obesity-associated low type-2 asthma, rather than establish diagnostic biomarkers. They mention that further validation is needed for the identified microRNA markers. The authors also address questions about the cell types responsible for the release of extracellular vesicles with different microRNA cargo in obese asthmatics. The study was supported by various funding sources and the authors declare no conflicts of interest. [Extracted from the article]