Back to Search
Start Over
Visible‐Light‐Mediated Photocatalyst‐Free Hydroacylation of Azodicarboxylic Acid Derivatives with 4‐Acyl‐1,4‐dihydropyridines.
- Source :
- Chinese Journal of Chemistry; Jun2024, Vol. 42 Issue 11, p1230-1236, 7p
- Publication Year :
- 2024
-
Abstract
- Comprehensive Summary: A visible‐light‐enabled, photocatalyst‐free hydroacylation reaction of azodicarboxylic acid derivatives was described. This radical conjugate addition (RCA) protocol relied on the dual role of 4‐acyl‐1,4‐dihydropyridine (acyl‐DHP) reagents that besides being as radical reservoirs, they also enabled the conversion of radical adducts to anion intermediates via reduction. Under "catalyst‐oxidant‐additive free" conditions, a wide range of structurally different acyl hydrazide products were readily obtained in 56%—99% yields. The utility of this transformation was further demonstrated by the scale‐up synthesis and downstream derivatization. [ABSTRACT FROM AUTHOR]
- Subjects :
- ACID derivatives
RADICAL anions
ACYLATION
DERIVATIZATION
AZO compounds
Subjects
Details
- Language :
- English
- ISSN :
- 1001604X
- Volume :
- 42
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- Chinese Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 176926998
- Full Text :
- https://doi.org/10.1002/cjoc.202300726