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Oral Microbiota of Infants in Maternal Gestational Diabetes: A Systematic Review.
- Source :
- Children; Apr2024, Vol. 11 Issue 4, p421, 12p
- Publication Year :
- 2024
-
Abstract
- Gestational diabetes mellitus (GDM) affects approximately 5–20% of pregnant women and is associated with adverse pregnancy outcomes. This review aimed to assess whether the oral microbiota of infants and their mothers with GDM had a different composition from that found in unaffected women and offspring. PubMed, Embase, Scopus, and Google Scholar were searched in December 2023 after protocol registration in the International Prospective Register of Systematic Reviews (CRD42023406505). Risk of bias was assessed using the Joanna Briggs Institute Critical Appraisal tools. Overall, 1113 articles were identified; after evaluating the full texts, 12 papers were included in the qualitative analysis. In six studies of the eight included, significant differences in microbiota between M-GDM and M-nGDM were found. In four studies, a depletion of Firmicutes and an enrichment of Proteobacteria was found in the microbiota of infants. Since all included studies were judged to have high risk of bias, a quantitative synthesis of the results was not carried out. In conclusion, although the oral microbiota of infants from mothers with GDM could be different from that of infants from mothers without GDM, there is insufficient evidence to clarify this aspect so far. [ABSTRACT FROM AUTHOR]
- Subjects :
- RNA analysis
ORAL microbiology
DNA analysis
SALIVA microbiology
MEDICAL information storage & retrieval systems
PREDIABETIC state
MICROBIAL sensitivity tests
DELIVERY (Obstetrics)
GESTATIONAL diabetes
CHILD health services
POLYMERASE chain reaction
HUMAN microbiota
PREGNANT women
DESCRIPTIVE statistics
SYSTEMATIC reviews
MEDLINE
BACTERIA
STATISTICS
ONLINE information services
DATA analysis software
SEQUENCE analysis
INTER-observer reliability
Subjects
Details
- Language :
- English
- ISSN :
- 22279067
- Volume :
- 11
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Children
- Publication Type :
- Academic Journal
- Accession number :
- 176903504
- Full Text :
- https://doi.org/10.3390/children11040421