Neuroendocrine Neoplasia: From Pathophysiology to Novel Therapeutic Approaches.

The document titled "Neuroendocrine Neoplasia: From Pathophysiology to Novel Therapeutic Approaches" provides an overview of neuroendocrine neoplasia (NEN) and its management and treatment. NENs are rare tumors that can occur in adults and children, with gastro-entero-pancreatic (GEP) and lung NENs being the most common types. The document emphasizes the importance of prognostic markers in determining treatment, such as tumor diameter, grading, and somatostatin receptor spectrum. It discusses the use of somatostatin analogues (SSAs) as standard therapy and the potential benefits of peptide receptor radionuclide therapy (PRRT). The authors of the article, Mara Carsote and Claudiu Nistor, both contributed to the research and writing of the manuscript, with Mara Carsote taking the lead in writing the original draft. The authors declare no conflicts of interest. [Extracted from the article]