Back to Search
Start Over
Topical oxygen therapy and singlet oxygen in wound healing: A scoping review.
- Source :
- International Wound Journal; Apr2024, Vol. 21 Issue 4, p1-25, 25p
- Publication Year :
- 2024
-
Abstract
- The aim of this scoping review was to provide an overview of current research into topical oxygen therapies including the under‐researched singlet oxygen for wound healing. A scoping review was undertaken using five databases. After duplicates and ineligible studies were excluded, 49 studies were included for a narrative review. Out of the included 49 studies, 45 (91.8%) were published in the past 10 years (2013–2023) with 32 (65.3%) published in the past 5 years (2018–2023). Eight of the studies were systematic reviews and/or meta‐analysis and 18 were RCTs. The search identified zero human RCTs on singlet oxygen, but one human cohort study and five studies in animals. There is evidence that topical oxygen therapy may be useful for the treatment of chronic wounds, mainly diabetic foot ulcers. Singlet oxygen has shown potential, but would need further confirmation in controlled human trials, including more research to understand the bio‐properties. [ABSTRACT FROM AUTHOR]
- Subjects :
- CUTANEOUS therapeutics
WOUND healing
MEDICAL information storage & retrieval systems
RESEARCH funding
OXYGEN therapy
CINAHL database
DESCRIPTIVE statistics
REACTIVE oxygen species
SYSTEMATIC reviews
MEDLINE
LITERATURE reviews
MEDICAL databases
WOUND care
DATA analysis software
CONFIDENCE intervals
Subjects
Details
- Language :
- English
- ISSN :
- 17424801
- Volume :
- 21
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- International Wound Journal
- Publication Type :
- Academic Journal
- Accession number :
- 176866363
- Full Text :
- https://doi.org/10.1111/iwj.14846