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Thermal segment microwell plate control for automated liquid handling setups.

Authors :
Seidel, Simon
Winkler, Katja F.
Kurreck, Anke
Cruz-Bournazou, Mariano Nicolas
Paulick, Katharina
Groß, Sebastian
Neubauer, Peter
Source :
Lab on a Chip; 4/21/2024, Vol. 24 Issue 8, p2224-2236, 13p
Publication Year :
2024

Abstract

Automated high-throughput liquid handling operations in biolabs necessitate miniaturised and automatised equipment for effective space utilisation and system integration. This paper presents a thermal segment microwell plate control unit designed for enhanced microwell-based experimentation in liquid handling setups. The development of this device stems from the need to move towards geometry standardization and system integration of automated lab equipment. It incorporates features based on Smart Sensor and Sensor 4.0 concepts. An enzymatic activity assay is implemented with the developed device on a liquid handling station, allowing fast characterisation via a high-throughput approach. The device outperforms other comparable devices in certain metrics based on automated liquid handling requirements and addresses the needs of future biolabs in automation, especially in highthroughput screening. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14730197
Volume :
24
Issue :
8
Database :
Complementary Index
Journal :
Lab on a Chip
Publication Type :
Academic Journal
Accession number :
176859904
Full Text :
https://doi.org/10.1039/d3lc00714f