Data on Drug Safety and Regulation Described by Researchers at IQVIA (Application of the target trial emulation framework to external comparator studies).

A new report discusses research findings on drug safety and regulation, specifically focusing on the use of external comparator (EC) studies to evaluate emerging pharmacological treatments for regulatory and health technology assessment purposes. The researchers from IQVIA propose the application of the target trial emulation (TTE) framework to improve the design and analysis of EC studies. The TTE framework involves emulating the key elements of an ideal target trial under real-world settings to generate more reliable evidence. The researchers describe how the TTE framework can enhance the clarity, transparency, and reliability of evidence generated from EC studies. [Extracted from the article]