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Contrast-specific propensity scores for causal inference with multiple interventions.

Authors :
Han, Shasha
Goh, Joel
Meng, Fanwen
Leow, Melvin Khee-Shing
Rubin, Donald B
Source :
Statistical Methods in Medical Research; May2024, Vol. 33 Issue 5, p825-837, 13p
Publication Year :
2024

Abstract

Existing methods that use propensity scores for heterogeneous treatment effect estimation on non-experimental data do not readily extend to the case of more than two treatment options. In this work, we develop a new propensity score-based method for heterogeneous treatment effect estimation when there are three or more treatment options, and prove that it generates unbiased estimates. We demonstrate our method on a real patient registry of patients in Singapore with diabetic dyslipidemia. On this dataset, our method generates heterogeneous treatment recommendations for patients among three options: Statins, fibrates, and non-pharmacological treatment to control patients' lipid ratios (total cholesterol divided by high-density lipoprotein level). In our numerical study, our proposed method generated more stable estimates compared to a benchmark method based on a multi-dimensional propensity score. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09622802
Volume :
33
Issue :
5
Database :
Complementary Index
Journal :
Statistical Methods in Medical Research
Publication Type :
Academic Journal
Accession number :
176812157
Full Text :
https://doi.org/10.1177/09622802241236952