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2, 1, 3‐Benzothiadiazole Derivative Small Molecule Fluorophores for NIR‐II Bioimaging.

Authors :
Hu, Zhen
Feng, Lili
Yang, Piaoping
Source :
Advanced Functional Materials; 4/18/2024, Vol. 34 Issue 16, p1-25, 25p
Publication Year :
2024

Abstract

Second near‐infrared (NIR‐II) bioimaging technology shows broad application prospects in the field of biomedical due to its significant superiority in deep tissue penetration and high signal‐to‐background ratio. Among them, organic small molecule fluorophores have received progressively more consideration due to their low biotoxicity, high biocompatibility, rapid clearance, and good modification properties. As the key acceptor core, 2, 1, 3‐benzothiadiazole (BTD) derivative plays an essential role in the construction of donor‐acceptor‐donor type NIR‐II fluorophores. This mini‐review summarizes the research development of NIR‐II small molecule fluorophores based on BTD derivatives in the field of bioimaging, focusing on molecular design and photophysical properties, and introduces a part of the applications in the biological field. Furthermore, the challenges of BTD‐based NIR‐II fluorophores in the future development and application are discussed. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1616301X
Volume :
34
Issue :
16
Database :
Complementary Index
Journal :
Advanced Functional Materials
Publication Type :
Academic Journal
Accession number :
176690692
Full Text :
https://doi.org/10.1002/adfm.202310818