Researchers' from Universidad Autonoma de Chile Report Details of New Studies and Findings in the Area of Nephropathy (Activation of Pannexin-1 channels causes cell dysfunction and damage in mesangial cells derived from angiotensin II-exposed...).

A new report discusses research findings on nephropathy, a prevalent health concern associated with chronic kidney disease (CKD) and hypertensive nephropathy. The study, conducted by researchers from Universidad Autonoma de Chile, focuses on the impact of Pannexin-1 (Panx1) channels on mesangial cell function in the context of hypertensive nephropathy. The researchers found that overactivation of Panx1 channels contributes to cellular dysfunction and damage in mesangial cells. The study provides valuable insights into the mechanisms by which angiotensin II negatively impacts mesangial cell function and contributes to renal damage in hypertensive nephropathy. [Extracted from the article]