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UDCA for Drug-Induced Liver Disease: Clinical and Pathophysiological Basis.

Authors :
Bessone, Fernando
Hillotte, Geraldine L.
Ahumada, Natalia
Jaureguizahar, Fernanda
Medeot, Anabela C.
Roma, Marcelo G.
Source :
Seminars in Liver Disease; Feb2024, Vol. 44 Issue 1, p1-22, 22p
Publication Year :
2024

Abstract

This article explores the potential benefits of using ursodeoxycholic acid (UDCA) as a treatment for drug-induced liver disease (DILI). DILI is a common adverse reaction to drugs that can lead to liver dysfunction and serious complications. UDCA has been used as a supportive drug in cholestatic DILI, but there is growing evidence suggesting its effectiveness in other forms of DILI as well. While there is limited research and international recommendations on the use of UDCA, case studies have shown promising results. Further research is needed to determine the optimal dosage and duration of UDCA treatment for DILI. [Extracted from the article]

Details

Language :
English
ISSN :
02728087
Volume :
44
Issue :
1
Database :
Complementary Index
Journal :
Seminars in Liver Disease
Publication Type :
Academic Journal
Accession number :
176635343
Full Text :
https://doi.org/10.1055/s-0044-1779520