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Echocardiographic features of right ventricle in septic patients with elevated central venous pressure.
- Source :
- BMC Anesthesiology; 4/4/2024, Vol. 24 Issue 1, p1-9, 9p
- Publication Year :
- 2024
-
Abstract
- Background: Elevated central venous pressure (CVP) is deemed as a sign of right ventricular (RV) dysfunction. We aimed to characterize the echocardiographic features of RV in septic patients with elevated CVP, and quantify associations between RV function parameters and 30-day mortality. Methods: We retrospectively reviewed a cohort of septic patients with CVP ≥ 8 mmHg in a tertiary hospital intensive care unit. General characteristics and echocardiographic parameters including tricuspid annular plane systolic excursion (TAPSE), pulmonary vascular resistance (PVR) as well as prognostic data were collected. Associations between RV function parameters and 30-day mortality were assessed using Cox regression models. Results: Echocardiography was performed in 244 septic patients with CVP ≥ 8 mmHg. Echocardiographic findings revealed that various types of abnormal RV function can occur individually or collectively. Prevalence of RV systolic dysfunction was 46%, prevalence of RV enlargement was 34%, and prevalence of PVR increase was 14%. In addition, we collected haemodynamic consequences and found that prevalence of systemic venous congestion was 16%, prevalence of RV-pulmonary artery decoupling was 34%, and prevalence of low cardiac index (CI) was 23%. The 30-day mortality of the enrolled population was 24.2%. In a Cox regression analysis, TAPSE (HR:0.542, 95% CI:0.302–0.972, p = 0.040) and PVR (HR:1.384, 95% CI:1.007–1.903, p = 0.045) were independently associated with 30-day mortality. Conclusions: Echocardiographic findings demonstrated a high prevalence of RV-related abnormalities (RV enlargement, RV systolic dysfunction and PVR increase) in septic patients with elevated CVP. Among those echocardiographic parameters, TAPSE and PVR were independently associated with 30-day mortality in these patients. [ABSTRACT FROM AUTHOR]
- Subjects :
- TRICUSPID valve
HEART diseases
RESEARCH funding
RETROSPECTIVE studies
TERTIARY care
DISEASE prevalence
DESCRIPTIVE statistics
SEPTIC shock
LONGITUDINAL method
VASCULAR resistance
CARDIAC output
CENTRAL venous pressure
MEDICAL records
ACQUISITION of data
INTENSIVE care units
RIGHT ventricular dysfunction
SYSTOLIC blood pressure
CONFIDENCE intervals
ECHOCARDIOGRAPHY
PROPORTIONAL hazards models
REGRESSION analysis
DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 14712253
- Volume :
- 24
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- BMC Anesthesiology
- Publication Type :
- Academic Journal
- Accession number :
- 176609856
- Full Text :
- https://doi.org/10.1186/s12871-024-02515-8