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Improvement of epilepsy secondary to acquired immunodeficiency syndrome with intestinal microbiota preparations: a case report.
- Source :
- Acta Epileptologica; 4/15/2024, Vol. 6 Issue 1, p1-6, 6p
- Publication Year :
- 2024
-
Abstract
- Background: Epilepsy secondary to acquired immunodeficiency syndrome (AIDS) can be challenging to manage. The potential interactions between antiretroviral drugs and antiepileptic drugs may result in the failure of both treatments. Therefore, it is crucial to develop more effective strategies to enhance the clinical outcomes of patients. Case presentation: We report a case of epilepsy secondary to AIDS. After administration of Bacteroides Fragilis 839 (BF839), the secondary generalized tonic-clonic seizures disappeared, the frequency of complex partial seizures decreased by 70%, and the duration of each episode was shortened. Additionally, long-term diarrhea associated with antiretroviral therapy for AIDS resolved, and the syphilis serofast reaction turned negative. No serious adverse reactions were observed during the three-year follow up. Conclusions: This case report suggests that the specific gut microbiota preparation could possibly improve refractory epilepsy in HIV patients while also potentially alleviating adverse reactions to antiretroviral drugs and concurrent syphilis infection. Our case may provide a new perspective for the treatment of HIV infection/AIDS. [ABSTRACT FROM AUTHOR]
- Subjects :
- THERAPEUTIC use of probiotics
EPILEPSY prevention
SYPHILIS prevention
ANTIBIOTICS
TREATMENT of epilepsy
DIARRHEA prevention
DIAGNOSIS of syphilis
HETEROCYCLIC compounds
DIARRHEA
GUT microbiome
ELECTROENCEPHALOGRAPHY
HIV-positive persons
TREATMENT effectiveness
SYPHILIS
EPILEPSY
SEIZURES (Medicine)
GRAM-negative anaerobic bacteria
ANTI-HIV agents
SERODIAGNOSIS
DISEASE relapse
PROBIOTICS
AIDS
DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 20969384
- Volume :
- 6
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Acta Epileptologica
- Publication Type :
- Academic Journal
- Accession number :
- 176584339
- Full Text :
- https://doi.org/10.1186/s42494-024-00156-5