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Supramolecular systems based on 2-hydroxyethylpiperidinium surfactants and BrijĀ® 35: aggregation behavior, solubilization properties, and antimicrobial activity.

Supramolecular systems based on 2-hydroxyethylpiperidinium surfactants and BrijĀ® 35: aggregation behavior, solubilization properties, and antimicrobial activity.

Authors :
Kushnazarova, R. A.
Mirgorodskaya, A. B.
Bekrenev, D. D.
Lyubina, A. P.
Lenina, O. A.
Petrov, K. A.
Voloshina, A. D.
Zakharova, L. Ya.
Source :
Russian Chemical Bulletin; Mar2024, Vol. 73 Issue 3, p536-545, 10p
Publication Year :
2024

Abstract

The aggregation behavior of mixed micellar solutions based on 2-hydroxyethylpiperidinium surfactants and nonionic surfactant Brij® 35 was investigated. The critical micelle concentrations determined by varying the component ratio suggest a negative deviation from the ideal mixing model (synergistic effect). It was demonstrated that the magnitude of the deviation from ideal mixing behavior depends on the alkyl chain length in the cationic surfactant and on the component ratio. The solubilization effect of the binary systems on hydrophobic substances was evaluated taking Orange OT dye and ibuprofen drug as examples. It was found that the piperidinium surfactants studied, both individually and in compositions containing up to 50% of the nonionic surfactant, exhibit high antimicrobial activity comparable to that of commercial antibiotics. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10665285
Volume :
73
Issue :
3
Database :
Complementary Index
Journal :
Russian Chemical Bulletin
Publication Type :
Academic Journal
Accession number :
176498638
Full Text :
https://doi.org/10.1007/s11172-024-4163-4