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Risk Factors for Death in Patients with Severe Acute Pancreatitis in Guizhou Province, China.
- Source :
- Gastroenterology Research & Practice; 4/1/2024, Vol. 2024, p1-8, 8p
- Publication Year :
- 2024
-
Abstract
- Aim. To compare the clinical characteristics of survival and nonsurvival patients with severe acute pancreatitis (SAP) and explore the risk of mortality in SAP patients. Methods. This was a single-center retrospective study performed in a severe acute pancreatitis diagnosis and treatment center. According to the outcome, SAP patients were divided into survival group and nonsurvival group. One-way ANOVA or independent t -test was used to compare the clinical characteristics of two groups of patients. Multivariate retrospective analysis was used to identify risk factors for mortality in SAP patients. Results. A total of 486 SAP patients were included in the study, and the 90-day mortality for SAP patients was 13.58%. The common etiologies of SAP are biliary tract diseases (69.75%) and hyperlipidemia (17.28%). The most common complications caused by SAP were organ failure (55.14%), ARDS (50.62%), AKI (30.45%), sepsis (27.16%), and abdominal fluid collection (27.57%). There were differences in age, complications, and medical intervention between the nonsurvival group and the survival group. The main causes of death were infection (46.97%), abdominal bleeding (28.79%), and organ failure (9.09%). The binary logistic regression analysis showed that there were significant differences in age, AKI, sepsis, abdominal hemorrhage, organ failure, laparotomy, creatinine, and APTT between the nonsurvival group and the survival group. Conclusion. Age, AKI, sepsis, abdominal hemorrhage, and organ failure are risk factors for mortality in SAP patients. SAP patients with high creatinine and prolonged APTT upon admission require doctors to be vigilant. The main cause of death in SAP patients is pancreatitis-related organ failure and secondary infection. [ABSTRACT FROM AUTHOR]
- Subjects :
- MORTALITY risk factors
RISK assessment
BILIOUS diseases & biliousness
ABDOMEN
ACUTE diseases
T-test (Statistics)
HYPERLIPIDEMIA
ADULT respiratory distress syndrome
CREATININE
LOGISTIC regression analysis
RETROSPECTIVE studies
DESCRIPTIVE statistics
MULTIVARIATE analysis
ACUTE kidney failure
AGE distribution
PANCREATITIS
ONE-way analysis of variance
SEPSIS
OVERALL survival
HEMORRHAGE
Subjects
Details
- Language :
- English
- ISSN :
- 16876121
- Volume :
- 2024
- Database :
- Complementary Index
- Journal :
- Gastroenterology Research & Practice
- Publication Type :
- Academic Journal
- Accession number :
- 176448393
- Full Text :
- https://doi.org/10.1155/2024/8236616