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Federal University Rio de Janeiro Researchers Provide New Data on Antiproliferative Activity (Cytotoxic and Antiproliferative Activity of LASSBio-2208 and the Attempts to Determine Its Drug Metabolism and Pharmacokinetics In Vitro Profile).
- Source :
- Drug Week; 4/12/2024, p819-819, 1p
- Publication Year :
- 2024
-
Abstract
- A recent study conducted by researchers at Federal University Rio de Janeiro in Brazil explored the antiproliferative activity of a compound called LASSBio-2208. The researchers found that LASSBio-2208 demonstrated moderate cytotoxic potency on certain cancer cell lines, but had no cytotoxic effect on healthy cells. Additionally, the compound exhibited a good antiproliferative effect on breast cancer cells and showed high metabolic stability in rat plasma. The study also investigated the potential synergistic effects of LASSBio-2208 when combined with other inhibitors. Further research is needed to fully understand the potential of LASSBio-2208 as a therapeutic agent. [Extracted from the article]
- Subjects :
- DRUG metabolism
PHARMACOKINETICS
RESEARCH personnel
Subjects
Details
- Language :
- English
- ISSN :
- 15316440
- Database :
- Complementary Index
- Journal :
- Drug Week
- Publication Type :
- Periodical
- Accession number :
- 176447219