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Federal University Rio de Janeiro Researchers Provide New Data on Antiproliferative Activity (Cytotoxic and Antiproliferative Activity of LASSBio-2208 and the Attempts to Determine Its Drug Metabolism and Pharmacokinetics In Vitro Profile).

Source :
Drug Week; 4/12/2024, p819-819, 1p
Publication Year :
2024

Abstract

A recent study conducted by researchers at Federal University Rio de Janeiro in Brazil explored the antiproliferative activity of a compound called LASSBio-2208. The researchers found that LASSBio-2208 demonstrated moderate cytotoxic potency on certain cancer cell lines, but had no cytotoxic effect on healthy cells. Additionally, the compound exhibited a good antiproliferative effect on breast cancer cells and showed high metabolic stability in rat plasma. The study also investigated the potential synergistic effects of LASSBio-2208 when combined with other inhibitors. Further research is needed to fully understand the potential of LASSBio-2208 as a therapeutic agent. [Extracted from the article]

Details

Language :
English
ISSN :
15316440
Database :
Complementary Index
Journal :
Drug Week
Publication Type :
Periodical
Accession number :
176447219