The new European Medicines Agency guideline on antidepressants: a guide for researchers and drug developers.

The European Medicines Agency (EMA) has released a new guideline on the clinical investigation of antidepressants. The guideline aims to improve the efficacy, safety, and personalization of these medications. It provides information on depressive disorders, clinical trial methodology, statistical analysis, and requirements for trials in difficult-to-treat populations. The guideline also discusses the use of psychedelics in depression treatment and highlights the need for randomized, double-blind, placebo-controlled trials. The ongoing consultation process will address remaining challenges in the field. [Extracted from the article]