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Bleeding and Perforation Complications after Follow-Up Colonoscopies in Faecal Immunochemical Test-Based Colorectal Cancer Screening: Insights from a Retrospective Case–Control Study.
- Source :
- Gastrointestinal Disorders; Mar2024, Vol. 6 Issue 1, p26-48, 23p
- Publication Year :
- 2024
-
Abstract
- Monitoring complications of colonoscopies after a positive faecal immunochemical test (FIT-colonoscopies) is crucial in FIT-based colorectal cancer (CRC) screening. We investigated the occurrence of bleeding and perforation post FIT-colonoscopies (2013–2019) in Flanders and the contributing factors. A retrospective case–control study was conducted, including bleeding/perforation cases within 14 days after index colonoscopy, and controls without such events. Bleeding rates dropped from 0.9–1.1% (pre-2017) to 0.3% (2017–2018) and further to 0.05% (2019), while perforation rates remained at 0.05–0.11% (2014–2019). Male gender, polypectomy, general anaesthesia, and recent antiplatelet/antithrombotic drug use increased bleeding odds. Incomplete colonoscopy, polypectomy, general anaesthesia, and recent antiplatelet/antithrombotic drug use raised perforation odds. The endoscopists (n = 16) with highest bleeding rates (top 5%) performed only 6% of total FIT-colonoscopies, yet their patients experienced 45.5% of bleeding events. Similarly, for the top 5% of perforation rates, endoscopists conducting only 4.5% of total FIT-colonoscopy had 49.0% of perforation events occur in their patients. This study sheds light on FIT-colonoscopy-related complications in Flanders, their rates and risk factors. These findings can be incorporated into CRC screening materials and guide interventions to mitigate complications. A central colonoscopy register is currently lacking in Belgium, highlighting the need for its establishment to facilitate recurrent monitoring and evaluation. [ABSTRACT FROM AUTHOR]
- Subjects :
- HEMORRHAGE risk factors
INTESTINAL perforation -- Risk factors
FECAL analysis
RISK assessment
POLYPS
IMMUNOCHEMISTRY
INTESTINAL perforation
RESEARCH funding
EARLY detection of cancer
SEX distribution
LOGISTIC regression analysis
COLORECTAL cancer
FIBRINOLYTIC agents
DESCRIPTIVE statistics
AGE distribution
MULTIVARIATE analysis
RETROSPECTIVE studies
EMAIL
STATISTICS
CASE-control method
PLATELET aggregation inhibitors
GENERAL anesthesia
CONFIDENCE intervals
DATA analysis software
COLONOSCOPY
HEMORRHAGE
Subjects
Details
- Language :
- English
- ISSN :
- 26245647
- Volume :
- 6
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Gastrointestinal Disorders
- Publication Type :
- Academic Journal
- Accession number :
- 176329421
- Full Text :
- https://doi.org/10.3390/gidisord6010003