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Alterations of Nutritional Status in Children and Adolescents with Acute Lymphoblastic Leukemia.
- Source :
- Children; Mar2024, Vol. 11 Issue 3, p334, 11p
- Publication Year :
- 2024
-
Abstract
- Malnutrition is often observed in pediatric cancer patients and has been recognized as a risk factor for relapse and survival. Maintaining an appropriate nutritional status during anticancer treatment has, therefore, been more and more frequently perceived as an additional requirement for optimal therapy outcomes. The aim of our study was to establish alterations of nutritional status in 26 children and adolescents treated for acute lymphoblastic leukemia (ALL) at the Children's Hospital in Zagreb, Croatia, between 2016 and 2021, by using anthropometric measures and serum albumin levels. The majority of patients (53.8% female, median 4 years, 52.2% intermediate-risk leukemia group) had normal weight at the beginning of chemotherapy. The percentage of overweight/obese patients increased from 4.2% at diagnosis to 37.5% at the end of intensive therapy. Apart from a significant increase in body weight (BW) and body mass index (BMI) for age, a notable decline in body height/body length (BH/BL) for age in the observed period was recorded, especially in high-risk leukemia patients. The alterations in serum albumin values were not significant, nor was their correlation with BMI. Dietary consultation was offered to all patients, while children with a decline in BMI and BH/BL received additional nutritional support. [ABSTRACT FROM AUTHOR]
- Subjects :
- BODY mass index
DATA analysis
NUTRITIONAL assessment
BODY weight
KRUSKAL-Wallis Test
CANCER patients
CHILDREN'S hospitals
MANN Whitney U Test
CANCER chemotherapy
STATURE
STATISTICS
FRIEDMAN test (Statistics)
LYMPHOBLASTIC leukemia
ANTHROPOMETRY
CHILDHOOD obesity
SERUM albumin
WEIGHT gain
DIET therapy
Subjects
Details
- Language :
- English
- ISSN :
- 22279067
- Volume :
- 11
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Children
- Publication Type :
- Academic Journal
- Accession number :
- 176304029
- Full Text :
- https://doi.org/10.3390/children11030334