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Participant completion of longitudinal assessments in an online cognitive aging registry: The role of medical conditions.

Authors :
Ashford, Miriam T.
Jin, Chengshi
Neuhaus, John
Diaz, Adam
Aaronson, Anna
Tank, Rachana
Eichenbaum, Joseph
Camacho, Monica R.
Fockler, Juliet
Ulbricht, Aaron
Flenniken, Derek
Truran, Diana
Mackin, Robert Scott
Weiner, Michael W.
Mindt, Monica Rivera
Nosheny, Rachel L.
Source :
Alzheimer's & Dementia: Translational Research & Clinical Interventions; Jan2024, Vol. 10 Issue 1, p1-11, 11p
Publication Year :
2024

Abstract

INTRODUCTION: This study aimed to understand whether older adults' longitudinal completion of assessments in an online Alzheimer's disease and related dementias (ADRD)–related registry is influenced by self‐reported medical conditions. METHODS: Brain Health Registry (BHR) is an online cognitive aging and ADRD‐related research registry that includes longitudinal health and cognitive assessments. Using logistic regressions, we examined associations between longitudinal registry completion outcomes and self‐reported (1) number of medical conditions and (2) eight defined medical condition groups (cardiovascular, metabolic, immune system, ADRD, current psychiatric, substance use/abuse, acquired, other specified conditions) in adults aged 55+ (N = 23,888). Longitudinal registry completion outcomes were assessed by the completion of the BHR initial questionnaire (first questionnaire participants see at each visit) at least twice and completion of a cognitive assessment (Cogstate Brief Battery) at least twice. Models included ethnocultural identity, education, age, and subjective memory concern as covariates. RESULTS: We found that the likelihood of longitudinally completing the initial questionnaire was negatively associated with reporting a diagnosis of ADRD and current psychiatric conditions but was positively associated with reporting substance use/abuse and acquired medical conditions. The likelihood of longitudinally completing the cognitive assessment task was negatively associated with number of reported medical conditions, as well as with reporting cardiovascular conditions, ADRD, and current psychiatric conditions. Previously identified associations between ethnocultural identity and longitudinal assessment completion in BHR remained after accounting for the presence of medical conditions. DISCUSSION: This post hoc analysis provides novel, initial evidence that older adults' completion of longitudinal assessments in an online registry is associated with the number and types of participant‐reported medical conditions. Our findings can inform future efforts to make online studies with longitudinal health and cognitive assessments more usable for older adults with medical conditions. The results need to be interpreted with caution due to selection biases, and the under‐inclusion of minoritized communities. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23528737
Volume :
10
Issue :
1
Database :
Complementary Index
Journal :
Alzheimer's & Dementia: Translational Research & Clinical Interventions
Publication Type :
Academic Journal
Accession number :
176273822
Full Text :
https://doi.org/10.1002/trc2.12438