Back to Search
Start Over
Effects of photodynamic therapy in patients with infected skin ulcers: A meta‐analysis.
- Source :
- International Wound Journal; Mar2024, Vol. 21 Issue 3, p1-11, 11p
- Publication Year :
- 2024
-
Abstract
- The purpose of the meta‐analysis was to evaluate and compare the photodynamic therapy's effectiveness in treating infected skin wounds. The results of this meta‐analysis were analysed, and the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) were calculated using dichotomous or contentious random‐ or fixed‐effect models. For the current meta‐analysis, 6 examinations spanning from 2013 to 2021 were included, encompassing 154 patients with infected skin wounds were the used studies' starting point. Photodynamic therapy had a significantly lower wound ulcer size (MD, −4.42; 95% CI, −7.56–−1.28, p = 0.006), better tissue repair (MD, −8.62; 95% CI, −16.76–−0.48, p = 0.04) and lower microbial cell viability (OR, 0.13; 95% CI, 0.04–0.42, p < 0.001) compared with red light exposure in subjects with infected skin wounds. The examined data revealed that photodynamic therapy had a significantly lower wound ulcer size, better tissue repair and lower microbial cell viability compared with red light exposure in subjects with infected skin wounds. However, given that all examinations had a small sample size, consideration should be given to their values. [ABSTRACT FROM AUTHOR]
- Subjects :
- MEDICAL information storage & retrieval systems
RESEARCH funding
WOUND infections
TREATMENT effectiveness
META-analysis
DESCRIPTIVE statistics
SYSTEMATIC reviews
MEDLINE
ODDS ratio
MEDICAL databases
PHOTODYNAMIC therapy
ONLINE information services
CONFIDENCE intervals
CELL survival
SKIN ulcers
MEDICAL care costs
Subjects
Details
- Language :
- English
- ISSN :
- 17424801
- Volume :
- 21
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- International Wound Journal
- Publication Type :
- Academic Journal
- Accession number :
- 176212922
- Full Text :
- https://doi.org/10.1111/iwj.14747