Researchers from Jinzhou Medical University Report Findings in Antioxidants (Rosmarinic Acid Improves Cyclophosphamide-induced Immunosuppression In Mice By Immunomodulatory and Antioxidant Effects).

Researchers from Jinzhou Medical University in China have conducted a study on the effects of rosmarinic acid (RA) on immune function in mice with cyclophosphamide-induced immunosuppression. The study found that RA improved the immune response by alleviating weight loss, increasing immune organ index, improving histopathological status, restoring peripheral blood levels, enhancing lymphocyte and natural killer cell activity, and promoting immune-related cytokine secretion. Additionally, RA improved oxidative stress and activated the PI3K/Akt signaling pathway. The researchers suggest that RA could be developed as an immunomodulator for functional food and nutraceutical applications. This research has been peer-reviewed. [Extracted from the article]