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Cyclodextrin derivatives decrease Transient Receptor Potential vanilloid 1 and Ankyrin 1 ion channel activation via altering the surrounding membrane microenvironment by cholesterol depletion.

Authors :
Nehr-Majoros, Andrea Kinga
Erostyák, János
Fenyvesi, Éva
Szabó-Meleg, Edina
Szőcs, Levente
Sétáló Jr, György
Helyes, Zsuzsanna
Szőke, Éva
Source :
Frontiers in Cell & Developmental Biology; 2024, p1-13, 13p
Publication Year :
2024

Abstract

This document is a list of references for a research article on the role of cyclodextrins in various biological processes. The references include studies on the solubilizing power of methyl-betacyclodextrins, the entry of fluorescently labeled methyl-beta-cyclodextrin into intestinal cells, the depletion of gangliosides and cholesterol by cyclodextrin derivatives, the effects of cyclodextrin-membrane interaction on drug delivery and membrane structure, the inhibitory effect of anandamide on sensory neuropeptide release, the antinociceptive effects of lipid raft disruptors, the effects of lipid raft disruptors on cell membrane fluidity, the analgesic effects of lipid raft disruption, the effect of cyclodextrin and membrane lipid structure on cyclodextrin-lipid interaction, the activation of capsaicin receptors by lipoxygenase products, the development of TRPV1-targeted drugs for pain conditions, the clearance of aggregated α-synuclein by TFEB activation, the cytotoxicity of beta-cyclodextrin derivatives, the regulation of membrane protein structure and function by lipid nano-environment, the depletion of cholesterol in model lipid membranes by cyclodextrin, the requirement of cholesterol for TRPV1 function and membrane expression, the effects of cyclodextrins on drug permeation through biological membranes, the molecular mechanism of cyclodextrin-mediated cholesterol extraction, the heterogeneity of lipid rafts, and [Extracted from the article]

Details

Language :
English
ISSN :
2296634X
Database :
Complementary Index
Journal :
Frontiers in Cell & Developmental Biology
Publication Type :
Academic Journal
Accession number :
176030278
Full Text :
https://doi.org/10.3389/fcell.2024.1334130