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Early treatment of type II SMA slows rate of progression of scoliosis.

Authors :
Coratti, Giorgia
Lenkowicz, Jacopo
Pera, Maria Carmela
D'Amico, Adele
Bruno, Claudio
Gullì, Consolato
Brolatti, Noemi
Pedemonte, Marina
Antonaci, Laura
Ricci, Martina
Capasso, Anna
Cicala, Gianpaolo
Cutrona, Costanza
de Sanctis, Roberto
Carnicella, Sara
Forcina, Nicola
Cateruccia, Michela
Damasio, Maria Beatrice
Labianca, Luca
Manfroni, Francesca
Source :
Journal of Neurology, Neurosurgery & Psychiatry; Mar2024, Vol. 95 Issue 3, p235-240, 6p
Publication Year :
2024

Abstract

A study published in the Journal of Neurology, Neurosurgery & Psychiatry examines the impact of early treatment on scoliosis progression in patients with type II spinal muscular atrophy (SMA). The study compares scoliosis progression between treated and untreated patients and identifies specific cut-off values that indicate how pharmacological treatment may slow down scoliosis progression. The findings suggest that early intervention with pharmacological treatment can delay the progression of scoliosis in type II SMA patients. These findings can guide clinicians in determining the optimal timing for treatment initiation and have implications for treatment guidelines and policies for SMA patients. [Extracted from the article]

Details

Language :
English
ISSN :
00223050
Volume :
95
Issue :
3
Database :
Complementary Index
Journal :
Journal of Neurology, Neurosurgery & Psychiatry
Publication Type :
Academic Journal
Accession number :
176024598
Full Text :
https://doi.org/10.1136/jnnp-2023-332084