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Long-term efficacy of selective arterial embolisation of renal angiomyolipoma.
- Source :
- Scandinavian Journal of Urology; 2023, Vol. 58 Issue 1, p86-92, 7p
- Publication Year :
- 2023
-
Abstract
- Objective: To evaluate the long-term efficacy of selective arterial embolisation in renal angiomyolipoma (AML), with emphasis on tumour shrinkage, potential regrowth and the necessity of supplementary procedures. Material and methods: A retrospective review of all 58 consecutive embolisations at two institutions, between 1999 and 2018, was performed. Clinical notes, laboratory data and imaging were reviewed. Results: The overall complication rate was 6.8%, with no Clavien-Dindo grades III-V complications. Kidney function was unaffected by embolisation as measured by creatinine. Median radiological follow-up was 4.8 years (interquartile range [IQR]: 2.8-7.8), and median clinical follow-up was 7.5 years (IQR: 4.7-14.0). Decreasing AML size was observed in 96% of procedures. Maximal shrinkage (30% median diameter decrease; IQR: 15-44) was reached after median 2.2 years (IQR: 0.6-4.8). During follow-up, regrowth occurred in 38% of patients, and four bleeding episodes occurred in three patients with tuberous sclerosis. Growing size and/or rebleeding prompted a redo embolisation in 9% of spontaneous AML and 50% of tuberous sclerosis-associated AML. Conclusions: Being a well-tolerated treatment with few complications, selective arterial embolisation renders a pronounced size-reduction in most patients with AML, and kidney function is preserved. Regrowth is common, and a radiological follow-up is necessary. Tuberous sclerosis is a risk factor for the need of reintervention. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 21681805
- Volume :
- 58
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Scandinavian Journal of Urology
- Publication Type :
- Academic Journal
- Accession number :
- 175977672
- Full Text :
- https://doi.org/10.2340/sju.v58.12318