Back to Search
Start Over
Subclinical cardiac impairments in fetuses conceived through assisted reproductive technology by speckle tracking echocardiography.
- Source :
- Journal of Perinatal Medicine; Mar2024, Vol. 52 Issue 3, p322-326, 5p
- Publication Year :
- 2024
-
Abstract
- To evaluate the changes of cardiac morphology and function in fetuses conceived through assisted reproductive technologies (ART) by speckle tracking echocardiography. A retrospective study was conducted in 101 spontaneously conceived (SC) fetuses and 99 ART-conceived ones. Fetal echocardiography was performed, fetal cardiac morphology and function were analyzed using two-dimensional speckle tracking software, including global sphericity index (GSI), global longitudinal strain (GLS), fractional area change (FAC) of the left and right ventricles, as well as segmental sphericity index (SI), end-diastolic diameter (ED), and fractional shortening (FS) in 24 segments. Compared to the SC fetuses, the ART-conceived fetuses exhibited decreased GSI (median [interquartile range], 1.22 [1.16–1.27] vs. 1.18 [1.11–1.24], p=0.007), decreased right ventricular GLS (24.9 [21.5–27.6] vs. 23.2 [20.4–26.8], p=0.026), and decreased right ventricular FAC (mean ± standard deviation, 39.7 ± 6.4 vs. 37.2 ± 7.1, p=0.003). Analysis of the 24 segments showed that ART-conceived fetuses had reduced SI in the apical segments of right ventricle and increased ED in several segments of the right ventricle. Fetuses conceived through ART had a more spherical shape of the global heart and predominantly right-sided cardiac remodeling and systolic function impairment. [ABSTRACT FROM AUTHOR]
- Subjects :
- HEART anatomy
CONGENITAL heart disease diagnosis
LEFT heart ventricle
ACADEMIC medical centers
T-test (Statistics)
VENTRICULAR remodeling
HEART
RETROSPECTIVE studies
DESCRIPTIVE statistics
MANN Whitney U Test
HUMAN reproductive technology
CONCEPTION
FETAL abnormalities
MEDICAL records
ACQUISITION of data
INTRACLASS correlation
CARDIAC contraction
RIGHT heart ventricle
DATA analysis software
COMPARATIVE studies
ECHOCARDIOGRAPHY
GLOBAL longitudinal strain
REGRESSION analysis
FETUS
Subjects
Details
- Language :
- English
- ISSN :
- 03005577
- Volume :
- 52
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Journal of Perinatal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 175872561
- Full Text :
- https://doi.org/10.1515/jpm-2023-0470