Studies from University Hospital Essen in the Area of Middle Cerebral Artery Infarction Described (Microvascular Network Remodeling in the Ischemic Mouse Brain Defined by Light Sheet Microscopy).

A new report from the University Hospital Essen discusses the analysis of microvascular networks in the reperfused ischemic brain using light sheet microscopy. The researchers examined microvascular network remodeling in mouse models of middle cerebral artery occlusion and the effects of a drug called FTY720 on this process. They found that microvascular networks in the ischemic brain did not return to their preischemic state but displayed a chronically altered pattern. The study concludes that this technology will significantly advance our understanding of microvascular restorative processes and could lead to new treatments for stroke. [Extracted from the article]