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Preferences for Long-Acting PrEP Products Among Women and Girls: A Quantitative Survey and Discrete Choice Experiment in Eswatini, Kenya, and South Africa.
- Source :
- AIDS & Behavior; Mar2024, Vol. 28 Issue 3, p936-950, 15p
- Publication Year :
- 2024
-
Abstract
- While oral pre-exposure prophylaxis (PrEP) can substantially reduce HIV risk, there are important barriers to uptake and adherence. We explored preferences for long-acting injectable and implantable PrEP among women and girls in Eswatini, Kenya, and South Africa. We conducted an online quantitative survey and discrete choice experiment (DCE) among adolescent girls (15–17), young women (18–29), and adult women (30–49). Participants completed a survey about their demographics and behavior and a DCE with 5 attributes (format, insertion location, number of insertions, dual-protection, and palpability). We recruited 1236 respondents (Eswatini = 420; Kenya = 350; South Africa = 493) in May 2022. Most participants were sexually active (72%), nearly 29% of whom reported recently engaging in transactional sex. 46% had heard of oral PrEP, but of those, only 16% reported having ever used it. Product format and dual-protection were significant predictors of product choice. Relative to a 2-month injection, participants had 1.76 times the odds (95% CI 1.08–2.04) of choosing a 6-month injectable, and 1.70 the odds (95% CI 1.06–1.92) of choosing a 12-month removable implant. Compared to a single-indication product, respondents had 2.46 times the odds (95% CI 1.04–2.68) of preferring a product also protecting against pregnancy, and 2.81 the odds (95% CI 1.04–3.05) of choosing a product that also protected against STIs. Adolescent girls and women in these countries showed strong preferences for longer-acting PrEP product formats, as well as those offering dual-protection. Introduction of long-acting options could improve PrEP uptake and reduce HIV burdens in east and southern African settings. [ABSTRACT FROM AUTHOR]
- Subjects :
- PREVENTION of sexually transmitted diseases
HIV prevention
THERAPEUTICS
INJECTIONS
CONFIDENCE intervals
ATTITUDE (Psychology)
TRANSACTIONAL sex
ANTIRETROVIRAL agents
CONTROLLED release drugs
CONSUMER attitudes
QUANTITATIVE research
PRE-exposure prophylaxis
QUALITATIVE research
COMPARATIVE studies
PSYCHOLOGY of women
DESCRIPTIVE statistics
HEALTH behavior
RESEARCH funding
DECISION making
UNPLANNED pregnancy
ADULTS
MIDDLE age
ADOLESCENCE
Subjects
Details
- Language :
- English
- ISSN :
- 10907165
- Volume :
- 28
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- AIDS & Behavior
- Publication Type :
- Academic Journal
- Accession number :
- 175676029
- Full Text :
- https://doi.org/10.1007/s10461-023-04202-0