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Managing Pediatric Asthma Exacerbations: The Role of Timely Systemic Corticosteroid Administration in Emergency Care Settings—A Multicentric Retrospective Study.
- Source :
- Children; Feb2024, Vol. 11 Issue 2, p164, 11p
- Publication Year :
- 2024
-
Abstract
- Background: Asthma is the most prevalent chronic respiratory condition in children. An asthma exacerbation (AE) is a frequent reason for emergency department (ED) visits. An important step in the management of a moderate to severe AE is the administration of systemic corticosteroids (SCS) within 1 h after ED presentation. This study aimed to determine the timing of SCS administration and correlate this with the length of stay and oxygen therapy duration and to explore factors predicting timely administration. Methods: This study used a retrospective multicenter observational design based on electronic medical records review. Children aged < 18 years, presenting to the ED with a moderate to severe AE were included. Results: 205 patients were included. Only 28 patients received SCS within 60 min after ED arrival. The median time to SCS administration was 169 min (Q<subscript>1</subscript> 92–Q<subscript>3</subscript> 380). A correlation was found between timing and oxygen treatment duration (r = 0.363, p < 0.001) and length of stay (r = 0.368, p < 0.001). No patient characteristics predicted timely SCS administration. Conclusions: Three in four children who presented with a moderate to severe AE at the ED did not receive SCS within the first hour. A prolonged timing of SCS administration correlated with a prolonged length of stay and extended need for oxygen support. [ABSTRACT FROM AUTHOR]
- Subjects :
- ASTHMA treatment
RESEARCH
LENGTH of stay in hospitals
KRUSKAL-Wallis Test
STATISTICS
HOSPITAL emergency services
ADRENOCORTICAL hormones
SCIENTIFIC observation
CONFIDENCE intervals
TIME
RETROSPECTIVE studies
ACQUISITION of data
TREATMENT duration
FISHER exact test
MANN Whitney U Test
TREATMENT effectiveness
TREATMENT delay (Medicine)
MEDICAL records
OXYGEN therapy
DESCRIPTIVE statistics
CHI-squared test
DATA analysis software
DATA analysis
ODDS ratio
DISEASE exacerbation
CHILDREN
Subjects
Details
- Language :
- English
- ISSN :
- 22279067
- Volume :
- 11
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Children
- Publication Type :
- Academic Journal
- Accession number :
- 175647712
- Full Text :
- https://doi.org/10.3390/children11020164