Infiltration analysis of eosinophils and basophils and co‐expression of CD69, CD63, IL‐31 and IgE in patients with bullous and non‐bullous pemphigoid.

This document presents the findings of a study on the presence of eosinophils and basophils in patients with bullous pemphigoid (BP) and non-bullous pemphigoid (NBP) skin. The study found that the number of eosinophils and basophils was significantly higher in BP lesional skin compared to BP perilesional skin and NBP skin. The activation of eosinophils and basophils in BP lesional skin was also observed. These findings suggest that eosinophils and basophils play an important role in the pathophysiology of BP and may contribute to the itch experienced by pemphigoid patients. Further research is needed to validate these findings. [Extracted from the article]