New tumor spatial mapping tool will help clinicians assess aggressiveness of cancer and personalize treatment.

Scientists from the Universities of Bath and Nottingham have developed a new AI tool called FuncOmap that maps the function of proteins in cancerous tumors. This tool allows clinicians to visualize the locations in the tumor where oncoproteins are interacting, providing more accurate diagnosis and informing personalized treatment for each patient. The researchers focused on clear cell renal cell carcinoma (ccRCC) and studied the function of Hypoxia-Induced Factor Alpha (HIF2a), a key target of ccRCC. The tool aims to improve patient stratification and enable personalized medicine. The study was funded by the UKRI Centre for Doctoral Training in Accountable Responsible and Transparent Artificial Intelligence (ART-AI) and is published in the journal BJC Reports. [Extracted from the article]