Findings from Seoul National University Update Understanding of Staphylococcus aureus (Egcg Inhibits Cystathionine Gamma-lyase Mccb From Staphylococcus Aureus By Making a Hemiacetal Compound With Pyridoxal Phosphate).

A recent study conducted at Seoul National University in South Korea has found that the natural compound EGCG can inhibit the enzyme MccB in Staphylococcus aureus, a gram-positive bacteria known for its multidrug resistance. The researchers discovered that EGCG forms a hemiacetal compound with pyridoxal phosphate, depleting the cytosolic pool of pyridoxal phosphate and inhibiting H2S production. This finding may have potential applications in diets aimed at suppressing the pathogenesis of S. aureus in the gut using EGCG. The research has been peer-reviewed and published in the journal Food Bioscience. [Extracted from the article]