Findings from Brigham and Women's Hospital in the Area of Autoimmunity Described (Lactate Limits Cns Autoimmunity By Stabilizing Hif-1a In Dendritic Cells).

A recent study conducted at Brigham and Women's Hospital in Boston, Massachusetts, explores the role of dendritic cells (DCs) in autoimmune disorders. The researchers identified a regulatory loop in DCs that limits immunopathology and developed a synthetic probiotic that activates this pathway for therapeutic purposes. The study highlights the potential of targeting DCs for the treatment of autoimmune diseases. The research was funded by various organizations, including the National Institutes of Health and the American Cancer Society. [Extracted from the article]