A systematic review on Streptomycetes mediated green synthesis gold nanoparticles and their application in nanomedicine.

Gold nanoparticles (AuNPs) are a preferred noble metal due to the fact that they have many different applications, including catalysis, nanoelectronics, and clinical practice. Applications for AuNPs include antitumor, gene delivery, and cancer treatment, drug delivery, catalysis, antioxidant, antimicrobial, and improving analytical performance. AuNPs are also used in biosensors, electronic devices, conducting, textiles, and surface-enhanced Raman spectroscopy. AuNPs can be easily synthesized using various techniques, depending on the desired shape and size. Their surfaces can be easily modified and attached with multiple molecules such as drugs, antibodies, protein, carbohydrates, and lipid. Numerous biological techniques, including those involving fungi, plants, bacteria and algae, were used to create AuNPs. There are various benefits to the biological synthesis of AuNPs, such as being simple, cost-effective, single-step, environmentally friendly, and less toxic to the cells. This review examined the role of Streptomycetes in synthesizing AuNPs from published articles and their application in the field of nanomedicine by searching PubMed, Google Scholar, and Web of Science database until June 2022. Finally, we summarize future prospect for green synthesized NPs as an alternative for nanomedicine. [ABSTRACT FROM AUTHOR]