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Anti-Diabetic Study of Flower Extract of Eugenia Jambolona In Rats.

Authors :
Devnani, Deepika
Dave, Pradeep C.
Acharya, Aparna Subhash
Pimpalshende, Pankaj Mohan
Katual, Manoj Kumar
Ghadi, Falgunee D.
Rahate, Sachin Shankar
Source :
Journal of Advanced Zoology; 2024, Vol. 45 Issue 1, p1201-1213, 13p
Publication Year :
2024

Abstract

We are learning more about the role that integrated medicine plays in treating metabolic illnesses. This is partially based on an abundance of scientific data regarding therapeutic herbs, including those with promise to treat diabetes, and in part on the WHO's and other governmental organizations' support for the practise. The anti-diabetic effect of number of flowers of Eugenia jambolana (EJA) was evaluated in the current study on streptozotocin-induced diabetic rats. The The study's primary goal was to look into the potential antidiabetic effects of subchronic oral administration of E. jambolana flowers infusion in rats with STZ-induced diabetes. In diabetic experimental rats, the floral extract considerably reduced blood sugar and cholesterol levels when given 400 mg/kg of body weight are the dosage. It also increased liver glycogen and total protein levels, enhanced reduced Hb1AC, serum level, and antioxidant levels, as well as impaired glucose tolerance. Additionally, it raised liver glycogen and total protein levels as well as glucose tolerance. A common hypoglycemic medication called Glibenclamide was used to compare the hypoglycemic efficacy.The preclinical investigation's results could be useful for phase 2 clinical studies that aim to reduce the morbidity and mortality of diabetes mellitus exacerbated by drug-induced hypoglycemia by implementing integrated medicine. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
02537214
Volume :
45
Issue :
1
Database :
Complementary Index
Journal :
Journal of Advanced Zoology
Publication Type :
Academic Journal
Accession number :
175541247