Right Ventricular Functions Can Predict Left Ventricular Reverse Remodeling in Patients with Ischemic Cardiomyopathy after Revascularization.

BACKGROUND: Left Ventricular reverse remodeling is a major indicator of functional improvement in patients with ischemic cardiomyopathy undergoing revascularization. We aimed to investigate the ability of right ventricular functions to predict left ventricular reverse remodeling (LVRR) in those patients. METHODS Subjects presented with ICM (n=52) were included and underwent right ventricular (RV) functions assessment. By the end of study patients were divided into two groups depending on positive LVRR response defined as =15% decrease in LV endsystolic volume (LVESV). Group 1 (n=28) with positive LVRR and group 2 (n= 24) without. RESULTS A significant difference between the two groups regarding right ventricular systolic tricuspid annular velocity (RV S'), RV myocardial performance index (RV MPI), RV free wall strain (RVFWS) and RV global longitudinal strain (RV GLS) was noticed. RV GLS was superior to RVFWS in prediction of LVRR (AUC difference of 0. 12, P= <0.001) and the later was superior to RV S' and RV MPI in the same regards. CONCLUSION: We conclude that right ventricular function may predict LVRR outcome of revascularization, with the RV GLS being the most powerful predictor. [ABSTRACT FROM AUTHOR]