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Bacteriophage-based approach for treatment of urinary tract infections: a quick outlook.

Authors :
GRYGORCEWICZ, BARTŁOMIEJ
GLIŹNIEWICZ, MARTA
JABŁOŃSKA, JOANNA
AUGUSTYNIAK, ADRIAN
OLSZEWSKA, PATRYCJA
WOJCIUK, BARTOSZ
MIŁEK, DOMINIKA
SERWIN, NATALIA
CZAJKOWSKI, ARTUR
CECERSKA-HERYĆ, ELŻBIETA
RAKOCZY, RAFAŁ
CYMBALUK-PŁOSKA, ANETA
Source :
APMIS; Feb2024, Vol. 132 Issue 2, p81-93, 13p
Publication Year :
2024

Abstract

Urinary tract infections (UTIs) are among the most common bacterial infections affecting millions worldwide. The increasing emergence of antibiotic-resistant bacteria has become a serious concern in managing UTIs. Therefore, there is a growing interest in using bacteriophages as an alternative or adjunct therapy for UTIs. Bacteriophages are viruses that infect and kill bacteria, making them a promising tool for treating UTIs caused by antibiotic-resistant bacteria. This article provides a quick outlook on using bacteriophages to treat UTIs. We summarize the current understanding of the biology of bacteriophages, the challenges associated with developing phage-based therapies, and the promising results of several case reports and clinical trials. We also highlight the potential of phage therapy as a valuable tool in the fight against antibiotic-resistant UTIs. This quick outlook on a bacteriophage-based approach for treating UTIs offers a timely and informative summary of the current research in this field. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09034641
Volume :
132
Issue :
2
Database :
Complementary Index
Journal :
APMIS
Publication Type :
Academic Journal
Accession number :
175321893
Full Text :
https://doi.org/10.1111/apm.13362