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A Multicenter Study of Clinical Outcomes and Volumetric Trends in Microprolactinomas.

Authors :
Hong, Christopher
Kilgallon, Jack
Sarkar, Sauradeep
Omara, Chady
Sajed, Sulaiman
Bakker, Leontine
Biermasz, Nienke
van Furth, Wouter
Verstegen, Marco
Lobatto, Daniel
Drexler, Richard
Flitsch, Jorg
Ricklefs, Franz
Ryba, Alice
Guaraldi, Federica
Min, Le
Smith, Timothy
Source :
Journal of Neurological Surgery. Part B. Skull Base; 2024 Supplement, Vol. 85, pS1-S398, 398p
Publication Year :
2024

Abstract

This article, titled "A Multicenter Study of Clinical Outcomes and Volumetric Trends in Microprolactinomas," explores the correlation between prolactin levels, tumor volumes, and clinical outcomes in patients with pituitary microadenomas. The study found that there was no significant correlation between prolactin levels and tumor volume at diagnosis. However, patients with higher tumor volumes tended to have higher prolactin levels. The article also discusses the different treatment options for microprolactinomas, including observation, medical therapy, and surgery. It concludes that tumors with higher prolactin levels may be more likely to undergo medical treatment, while tumors with lower levels may be suitable for surveillance as they tend to shrink over time. The article suggests that an elevated baseline PRL/volume ratio may indicate tumor growth that may require intervention. [Extracted from the article]

Details

Language :
English
ISSN :
21936331
Volume :
85
Database :
Complementary Index
Journal :
Journal of Neurological Surgery. Part B. Skull Base
Publication Type :
Academic Journal
Accession number :
175285756
Full Text :
https://doi.org/10.1055/s-0044-1780165